MSC Exosome Concentrate, 1 and 5 mL
MSC exosomes in normal saline, for the laser and microneedling suite.
MSC exosomes in normal saline, in 1.0 mL and 5.0 mL vials of 1 trillion and 5 trillion microvesicles, as stated by the manufacturer.
Manufactured by a qualified partner manufacturer. Supplied by ExaVeyra Sciences to licensed clinics.
- Up to 5 trillion microvesicles per vial
- Frozen cold-chain delivery
- Lot certificate of analysis on request
Available formats
Each format has its own reference number. Figures are as stated by the manufacturer; lot-specific values are on the certificate of analysis.
| Format | Reference | Manufacturer-stated content per vial |
|---|---|---|
| MSC Exosome Concentrate 1.0 mL | EXV-MEC-01 | 1 trillion microvesicles |
| MSC Exosome Concentrate 5.0 mL | EXV-MEC-05 | 5 trillion microvesicles |
Where it fits in your suite
Practices place the concentrate as the topical finishing step of a skin session, applied to the skin once the device work is complete.
After microneedling
Applied topically once the microneedling pass is complete.
After fractional laser
Applied topically as the closing step of a fractional laser session.
After RF microneedling
Applied topically after radiofrequency microneedling, as the final step of the session.
This describes where practices place it in a session, not what it does. Whether and how it is used is the licensed practitioner's decision.
What sets it apart
Qualified partner manufacturer
Manufactured by a qualified partner manufacturer and shipped in the manufacturer's labeled packaging.
Lot certificate of analysis on request
Every lot is issued a certificate of analysis, provided on request before or with your order.
Frozen cold-chain delivery
Shipped frozen on cold chain. Stored at -20°C long term and 4°C once thawed, per the manufacturer's handling instructions.
Lot traceability
Every vial carries its lot number, which ties it to that lot's certificate of analysis.
What's in the vial
MSC Exosome Concentrate is a mesenchymal stromal cell (MSC)-derived exosome preparation in normal saline. Each 1.0 mL vial contains approximately 1 trillion microvesicles and each 5.0 mL vial approximately 5 trillion, as stated by the manufacturer; the finished product is a cell-free vesicle formulation, not a stem cell product.
Exosomes are cell-free lipid-bilayer nanovesicles (30-150 nm) carrying signaling cargo including microRNAs, growth factors and membrane proteins, released by parent cells and characterized by particle count and size.
Manufactured by a qualified partner manufacturer, with a certificate of analysis issued for every lot and available on request.
Characterization
Particle count and size · lot certificate of analysis
Request or reserve MSC Exosome Concentrate
MSC Exosome Concentrate 1.0 mL
1 trillion microvesicles
Ref: EXV-MEC-01
MSC exosomes in normal saline, in a single 1.0 mL vial. Manufactured by a qualified partner manufacturer. Cold-chain shipped.
MSC Exosome Concentrate 5.0 mL
5 trillion microvesicles
Ref: EXV-MEC-05
5.0 mL format for larger surface areas; the 1.0 mL format suits smaller application areas. Cold-chain shipped.
How every lot is tested
Each lot of exosome material is documented by a certificate of analysis that covers three stages, from the tissue donor to the finished vial. The tests are listed here; the acceptance criteria and results are shared with verified practices on request.
Donor screening
The placental tissue donor is screened before any cells are banked.
- Microbial testing with strain typing
- HIV-1 and HIV-2, by antibody and nucleic acid testing
- Hepatitis B, by core antibody, surface antigen and nucleic acid testing
- Hepatitis C, by antibody and nucleic acid testing
- HTLV I and II
- Syphilis
- West Nile virus
- Cytomegalovirus
- Risk assessment for Zika, Ebola, malaria, Chagas disease and CJD
Cell bank safety
The master cell bank is tested for contamination and adventitious agents.
- Sterility by membrane filtration
- Mycoplasma
- Adventitious viruses, in vitro on three cell lines and in vivo
- Bovine and porcine agents
- Hepatitis A, B and C
- HIV-1 and HIV-2, and HTLV I and II
- Cytomegalovirus and human herpesviruses
- Parvovirus B19 and papillomavirus
Final vial release
Every lot of finished vials is tested before release.
- Sterility by direct inoculation
- Endotoxin
- Mycoplasma
- Zika virus, JC virus and SARS-CoV-2
- Vesicle particle size
- Particle count per vial
- CD81 identity by Western blot
- Purity by SEC-HPLC
- Total RNA concentration
- Osmolality and pH
- Appearance
A certificate of analysis is issued for every lot and provided on request. Requests are reviewed for NPI-verified practices in the practitioner portal.
A concierge service for standing accounts
Verified clinics that order on a schedule are looked after by name. Allocation, reorders and paperwork are handled for you, so the vial is in the freezer before the session is on the book.
Dedicated contact
One named person at ExaVeyra handles your account, from verification to every reorder.
Priority allocation
Standing accounts are first in line when a new lot is allocated.
Standing orders
Set a recurring order on your schedule and it ships on cold chain without a new request each time.
Documentation sessions
A walkthrough for your team of lot certificates, storage and handling records.
Choose your signature
Three vials in the collection, each with its own place in the suite.
MSC Exosome Concentrate, High Load
The highest microvesicle load in the collection.
View MSC Exosome Concentrate, High Load
Placental MSC Secretome
The whole conditioned medium, in one vial.
View Placental MSC SecretomeCompare the collection
The concentrates and the secretome side by side: formats, content per vial and where each one fits.
Regulatory & handling
Cold-chain shipped frozen. Stored at −20°C long term and 4°C once thawed, per the manufacturer's handling instructions. Supplied for topical aesthetic use by licensed practitioners, as labeled by the manufacturer, and for laboratory and IND-authorized clinical research. Not sold for injection, infusion or any other route into the body, and not intended to diagnose, treat, cure or prevent any disease.
Frequently asked questions
- How does the MSC Exosome Concentrate differ from the other exosome products?
- It is purified MSC exosomes in normal saline, without the amino acids of the high-load concentrate or the serum base of the skincare serum. Each lot is issued a certificate of analysis, available on request.
- What documentation ships with an order?
- Every vial carries its lot number, and a Certificate of Analysis is issued for every lot and provided on request. Practices with their own documentation requirements should raise them at account setup so we can confirm what we are able to supply before a first order ships.
- How should this material be handled on arrival?
- Check the temperature indicator included with the shipment before the vials go into storage, and move them to their storage condition promptly. If the indicator reads outside range, contact us before use rather than storing the shipment. Storage and handling conditions follow the manufacturer's handling instructions, which ship with each order.
- Who can open a wholesale account?
- NPI-verified licensed practitioners. Verification happens before pricing is released, and professional licensure is confirmed for the destination state before a first order ships.
- What is the regulatory status of this material?
- No exosome product has been approved by the FDA for administration to humans. Material is supplied for topical aesthetic use in clinics and for medical, molecular biology and biochemistry research applications, and is not a tissue product as defined by FDA guidelines. Whether and how it is used in a given session is the licensed practitioner's decision.
Ready to order MSC Exosome Concentrate?
NPI-verified wholesale accounts unlock full pricing across every format. Request a quote for any format above or apply for a full wholesale account.
Important regulatory notice
Product status. Biomolecular signaling vesicles (exosomes) supplied by ExaVeyra Sciences are not approved, cleared, or licensed by the United States Food and Drug Administration. No exosome product has been approved by the FDA for administration to humans for any indication. Statements on this page have not been evaluated by the FDA.
Use and responsibility. Supplied for topical aesthetic use by licensed practitioners, as labeled by the manufacturer, and for laboratory and IND-authorized clinical research. Not for injection, infusion, intranasal or any other route into the body. The licensed practitioner is solely responsible for whether, how and in what setting the material is used.