Sourcing Exosomes in Texas
Licensed Texas practices order Kimera exosome material from ExaVeyra for topical aesthetic use, shipped frozen from Florida with a Certificate of Analysis and lot traceability on every vial. Texas buyers need their own professional license and NPI; the wholesale distribution license is the supplier’s obligation, not the purchaser’s.
Two Texas specifics shape how practices set this up. Texas applies the corporate practice of medicine doctrine, so who owns the practice matters. And the Texas Medical Board rewrote its delegation rules in January 2025, moving them out of chapter 193 and into chapter 169.
At a glance
| Question | Answer |
|---|---|
| Does ExaVeyra ship to Texas? | Yes. Shipped frozen from Florida, as we do to all 50 states |
| Cold-chain shipping from Florida | Overnight shipping; arrival can take 1 to 3 business days |
| State regenerative-medicine statute | HB 810 (2017) |
| Does that statute reach exosomes? | No. Its definition is written around cells; exosomes are acellular and governed federally |
| Physician delegation required to hand off medical acts | Yes |
| Who holds the licensure to ship into the state | The pharmacy partner and the tissue bank that ship, not the purchasing practice |
| What ExaVeyra supplies here | Kimera exosome material; compounded preparations available through the 503A pharmacy partner |
| Last reviewed | 9 August 2026 |
Ordering from Texas
ExaVeyra ships to licensed practices in all 50 states, Texas included. Licensure for shipping into the state is held by the entities that ship: our 503A pharmacy partner holds nonresident pharmacy licenses in 33 jurisdictions, including Puerto Rico, and exosome material ships from a registered tissue bank licensed to ship to all 50 states and Puerto Rico. Your practice orders against its own professional license and NPI and needs no wholesale permit to purchase.
What your practice provides
- An active Texas professional license in good standing, verifiable through the relevant board.
- A valid NPI, which ExaVeyra verifies at account setup.
- A signed professional-use acknowledgment on file for exosome material.
- A Texas Sales and Use Tax Resale Certificate (form 01-339) if the practice is purchasing for resale rather than for use in its own operations. The certificate goes to the supplier, not to the Comptroller.
How the state permits wholesale distribution
Texas licenses wholesale drug distribution through DSHS rather than the medical or pharmacy board, and both in-state and out-of-state distributors shipping into Texas fall under chapter 431. The state rules adopt the federal wholesale distribution requirements at 21 C.F.R. part 205 by reference, and licensed distributors post a surety bond. Licensing sits with the distributor; a purchasing practice is not the license holder.
Tex. Health & Safety Code ch. 431, subch. N; 25 Tex. Admin. Code §§ 229.419 to 229.430 · Texas Department of State Health Services, Drugs and Medical Devices Group
Texas regenerative-medicine law
Texas enacted HB 810, codified at Tex. Health & Safety Code ch. 1003, effective 1 September 2017.
Physicians treating patients with a severe chronic disease or terminal illness, where the treatment is under investigation in a clinical trial. The chapter sets conditions around patient eligibility and informed consent, and a 2019 amendment adjusted the treatment of adult stem cells used for homologous purposes.
- Severe chronic disease
- Terminal illness
“an adult stem cell treatment that: (A) is under investigation in a clinical trial and being administered to human participants in that trial; and (B) has not yet been approved for general use by the United States Food and Drug Administration”
How this applies to exosomes
Texas HB 810 is often cited as the reason exosome services are permitted in Texas. It is not. Chapter 1003 defines an investigational stem cell treatment as an adult stem cell treatment under investigation in a clinical trial that the FDA has not approved for general use. It is a stem cell framework tied to enrolled clinical trials, and it does not address acellular extracellular vesicles at all, either to permit or to restrict them. Exosome products remain governed by federal law, under which no exosome product has been approved by the FDA for administration to humans. ExaVeyra supplies Kimera material for topical aesthetic use by licensed practitioners, with full COA and lot documentation.
Who can handle product in a Texas practice
Delegation in Texas moved in January 2025. The Texas Medical Board repealed chapter 193 on standing delegation orders, including the former rule 193.17 covering non-surgical medical cosmetic procedures, and consolidated delegation into 22 Texas Administrative Code chapter 169, with other delegated acts at sections 169.25 to 169.28. Published med spa guidance still frequently cites 193.17, which no longer exists. Delegation is documented through written standing delegation orders, standing medical orders, protocols, or prescriptive authority agreements.
| Role | Scope under state law |
|---|---|
| MD / DO | Physicians licensed by the Texas Medical Board may perform medical acts within their scope and are the source of any delegation. Non-surgical medical cosmetic procedures are the practice of medicine in Texas, so they must be properly delegated and supervised rather than simply assigned. |
| NP / APRN | Advanced practice registered nurses practice under a prescriptive authority agreement with a delegating physician, within the scope that agreement establishes. |
| PA | Physician assistants practice under a prescriptive authority agreement with a supervising physician, within the delegated scope. |
| RN | Registered nurses may perform delegated medical acts under a physician’s written protocol and supervision. The Texas Medical Board expects an appropriately trained physician, or a properly supervised mid-level practitioner, to perform the patient assessment and issue the order for a medical cosmetic procedure; an RN does not order the procedure independently. |
Good faith examination
Texas requires an appropriate patient assessment and a physician order before a non-surgical medical cosmetic procedure. The Texas Medical Board expects that assessment to be performed by an appropriately trained physician or a properly supervised mid-level practitioner. Separately, House Bill 3749, known as Jenifer’s Law and effective 1 September 2025, restricts who may administer elective intravenous therapy to physicians, physician assistants, advanced practice registered nurses, and registered nurses, and limits prescribing delegation to PAs and APRNs under physician supervision. It governs elective IV therapy rather than topical application, but it applies to many practices that also offer aesthetic services.
Ownership and clinic licensing
In practice this means non-physicians generally cannot own an entity that delivers medical services or control its clinical decisions, and aesthetic procedures amounting to the practice of medicine sit inside that rule. Texas practices commonly address it through a professional entity owned by a licensed physician alongside a separate management services arrangement. Structure this with Texas counsel before opening.
Cold chain into Texas
Shipments leave Florida frozen under validated temperature monitoring. A package in transit over a weekend waits in the carrier network, so practices in Texas order around weekend and holiday closures.
| Metro | County | Notes |
|---|---|---|
| Houston | Harris | Largest Texas market, with a deep concentration of aesthetic and regenerative practices. |
| Dallas | Dallas | Dense med spa corridor and a large concierge and longevity segment. |
| Austin | Travis | Fast-growing aesthetic and longevity market. |
| San Antonio | Bexar | Broad mix of dermatology, orthopedic, and aesthetic practices. |
| Fort Worth | Tarrant | Metroplex market served alongside Dallas. |
| El Paso | El Paso | West Texas market with cross-border patient flow. |
- Texas orders of fifteen or more cold-chain units ship free nationwide; see the volume program for current thresholds.
Wholesale exosome supply by city in Texas
Each city page covers local receiving conditions, delivery disruptions and business license rules for Texas practices in that area.
Practice types we supply in Texas
Texas licensing and verification
Texas sourcing questions
- Does Texas HB 810 let my practice offer exosome treatments?
- No. Chapter 1003 of the Texas Health and Safety Code defines an investigational stem cell treatment as an adult stem cell treatment under investigation in a clinical trial that the FDA has not approved for general use, for patients with a severe chronic disease or terminal illness. Exosomes are acellular and fall outside that definition, so the chapter neither permits nor restricts them. Exosome products are governed federally, and no exosome product is FDA-approved for administration to humans.
- Is TMB rule 193.17 still the delegation rule for cosmetic procedures?
- No. The Texas Medical Board repealed chapter 193, including rule 193.17, in January 2025 and consolidated delegation into 22 Texas Administrative Code chapter 169, with other delegated acts at sections 169.25 to 169.28. A lot of published med spa guidance still cites 193.17. Check your protocols against chapter 169.
- Can a non-physician own a med spa in Texas?
- Texas applies the corporate practice of medicine doctrine, so non-physicians generally cannot own a practice delivering medical services or control clinical decisions, and non-surgical medical cosmetic procedures are the practice of medicine in Texas. Practices commonly use a physician-owned professional entity with a separate management services arrangement. Structure this with Texas counsel.
- Does my Texas clinic need a wholesale distributor license to buy exosomes?
- No. The Texas wholesale drug distributor license under chapter 431 is held by the distributor shipping into the state, not by the practice buying. Your practice orders against its own professional license and NPI. Licensure for shipping into the state is held by the entities that ship: our 503A pharmacy partner for compounded preparations, and a registered tissue bank licensed to ship to all 50 states and Puerto Rico for exosome material.
- Does Jenifer’s Law affect exosome use?
- House Bill 3749, known as Jenifer’s Law and effective 1 September 2025, governs elective intravenous therapy. It restricts administration to physicians, physician assistants, advanced practice registered nurses, and registered nurses, and limits prescribing delegation to PAs and APRNs under physician supervision. It addresses IV therapy rather than topical application, but it applies to many Texas practices that also offer aesthetic services.
- How long does cold-chain shipping take to Texas?
- Ships from Florida by overnight shipping, and arrival can take one to three business days. All exosome shipments travel cold-chain with validated temperature monitoring. A shipment in transit over a weekend waits in the carrier network, so a practice that will be closed orders around the closure.
Sources
Last reviewed 9 August 2026 by ExaVeyra Sciences editorial team. Every claim above links to a primary source.
- Tex. Health & Safety Code ch. 1003, Adult Stem Cells (accessed 8 August 2026)
- Tex. Health & Safety Code ch. 431, subch. N, wholesale distributors of prescription drugs (accessed 8 August 2026)
- Texas DSHS, prescription drug distributor licensing (accessed 8 August 2026)
- Texas Medical Board rules, 22 Tex. Admin. Code ch. 169 (accessed 8 August 2026)
- Texas HB 3749 (89th Legislature), Jenifer’s Law (accessed 8 August 2026)
- Texas Comptroller, sales and use tax resale certificates (accessed 8 August 2026)
- FDA Public Safety Notification on Exosome Products (accessed 8 August 2026)
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. There are no FDA-approved exosome products. Biomolecular signaling vesicle products distributed by ExaVeyra Sciences are supplied for topical aesthetic use by licensed practitioners and for laboratory and IND-authorized clinical research, and are not tissue products as defined by FDA guidelines.