The molecular biology of mesenchymal stromal cells
Mesenchymal stromal cells sense their environment and answer with secreted proteins, metabolic enzymes, vesicles and even whole organelles. The molecules behind that exchange are well characterized and can be measured.
These references describe that biology molecule by molecule, building on the stromal cell marker panel in the surface receptor references, with numbered citations to the peer-reviewed literature.
The references, in reading order
0 of 4 published. The remainder are in review and will appear as they are completed.
How stromal cells signal
The enzymes and secreted proteins stromal cells use to communicate, and how the surrounding environment tunes them.
MSC Immunomodulation Biochemistry: IDO, PGE2 and TSG-6
Three molecules behind stromal immune signaling.
In review
MSC Licensing and Preconditioning: IFN-γ, TNF-α and Hypoxia
How the environment reshapes stromal cells.
In review
What stromal cells share and how they differ
Organelle transfer between cells, and the subpopulations single-cell sequencing has resolved within stromal cell cultures.
Mitochondrial Transfer by Mesenchymal Stromal Cells
Organelle transfer between cells.
In review
Mesenchymal Stromal Cell Heterogeneity by Single-Cell RNA-seq
Subpopulations at single-cell resolution.
In review
These references describe protein biochemistry and normal cell biology for licensed practitioner education, and make no statement about the composition of any product. They are not medical advice or regulatory guidance. There are no FDA-approved exosome products. Biomolecular signaling vesicle products distributed by ExaVeyra Sciences are supplied for topical aesthetic use by licensed practitioners and for laboratory and IND-authorized clinical research, are not intended to diagnose, treat, cure, mitigate or prevent any disease, and are not tissue products as defined by FDA guidelines.